A satisfying answer on how to choose essential oil products?

With a restriction of antibiotics in feed has been nationally announced, finding a feed antibiotics replacement is now looming ahead.

Essential oil products play an important role in the replacement of antibiotics as antibacterial, growth-promoting, and immune regulation etc, are of its functions. Then how do we make a right selection over Essential oil products? We suppose every step of the whole process, from the screening of raw materials in the laboratory to the validation of results of animal experiments are quite vital. 

R & D of EssoGut

Step 1. Screening natural raw materials with effective bacteriostasis (bacteriostatic test and cell culture)

Step 2. Screening and compatibility stability of compound combinations (bacteriostatic test and cell culture)

Step 3. Running retention rate test to determine storage and processing stability

Step 4. Running animal test to determine the combination and dosage (pig, poultry)

Step 5. Improving product process and developing new products.

Screening of raw materials and compatibility

After running bacteriostatic and cell culture test , the products with strong bacteriostasis and little toxicity to intestinal epithelial cells will be screened out.

If we inoculate E.coli K88 and essential oil onto cultured pig intestinal epithelial cells at the same time, LDH(lactate dehydrogenase) will stay in a negative activity condition as we can see from the information stated in the form above, and we all know LDH was positively correlated with the number of cell death. So that is to say E.coli will act a low level of toxicity function on intestinal epithelial cells, due to the inhibitory of activity taken effected  in E. Coli by essential oils (compound essential oil 1 is EssoGut ).

Retention test

Multilayer coating technology assures a strong stability of EssoGut, while in the mean time a high retention rate will be obtained even under 100℃.

Feeding test

Effect of EssoGut Substituting Colistin sulfate on Growth Performance of Weaned Piglets

Test animals:  (28±1d) weaned piglets

Conclusion: The growth performance of EssoGut group stands out evidently while the antidiarrheal effect is comparable to that of colistin sulfate group, and EssoGut comprehensively outmatches other compound essential oils.

Effect of EssoGut Substituting chlortetra’cycline on Growth Performance of Broilers

Test animals: AA broilers

Conclusion: EssoGut is neck and neck with chlortetracycline in promoting daily feed intake of broiler chickens, and has a better performance on average daily weight gain, feed-to-weight ratio, and reduction of death rate.

EssoGut is a natural plant essential oil product with a less pungent smell, high integrity of capsule, high dissolution, high utilization rate, monitorable content and better immune enhancement effect.

Since 2002, Hubei Horwath Bio. has been committed to research and development of green and antibiotics-free feed additives for animal gut health. We provide a series of fine products to our clients which include short and medium chain fatty acid esters (Eucalorie--tributyrin, OmniGuard--α-GML), natural plant essential oil (EssoGut), botanical astringent (HerbGut, MustAdd), microecologics (UBIQUITIN), organic acid (Acids-4-gut) and sweetener, etc. 

It’s impractical that antibiotics can be fully replaced by any solitary substance that exists, so we will address ourselves to offer targeted solutions of feed antibiotics replacement aimed at different animal species, different growth stages, and different breeding management levels.